Alisma plantago-aquatica: Traditional Herb for Water Metabolism, Kidney Health, and Inflammation Relief

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Alisma plantago-aquatica, commonly known as Water Plantain, is a perennial aquatic herb from the Alismataceae family. It thrives in wetlands and shallow waters, and its rhizome has been used for centuries in TraditionalMedicine, where it is called Ze Xie.

Traditionally valued for promoting urination, clearing dampness, and supporting kidney and urinary tract health, Alisma plantago-aquatica is now also studied for its diuretic, anti-inflammatory, antioxidant, and lipid-lowering effects.

Phytochemical Composition

The rhizomes of Alisma plantago-aquatica contain a rich array of bioactive compounds:

• Triterpenes (e.g., alisol A, alisol B): Provide diuretic, lipid-lowering, and anti-inflammatory effects.
• Sesquiterpenes: Contribute to immune-modulating actions.
• Polysaccharides: Support antioxidant defenses and general health.
• Sterols and Flavonoids: Enhance vascular protection and reduce oxidative stress.

5 Key Health Benefits of Alisma plantago-aquatica

1. Water Metabolism and Diuretic Effects

Alisma is traditionally used to promote urination and drain dampness. Modern research confirms its potent diuretic effect, making it valuable for reducing edema, relieving urinary difficulties, and supporting detoxification (Wang et al., 2018).

2. Kidney and Urinary Tract Support

By promoting fluid metabolism and reducing urinary tract inflammation, Alisma plantago-aquatica supports kidney health and may help prevent urinary tract infections, kidney stones, and nephritis (Zhou et al., 2020).

3. Anti-inflammatory and Immune Modulation

The herb's triterpenes and sesquiterpenes suppress pro-inflammatory markers like TNF-α and IL-6, supporting its use in managing inflammatory conditions such as arthritis, dermatitis, and chronic kidney inflammation.

4. Antioxidant and Liver Protection

Alisma's antioxidant compounds protect liver cells against oxidative stress, support detoxification pathways, and may help prevent hepatic steatosis (fatty liver disease) (Liu et al., 2022).

5. Cardiometabolic Health and Lipid Balance

Triterpenoids from Alisma lower serum cholesterol, triglycerides, and LDL levels while enhancing HDL cholesterol. This supports heart health and metabolic balance, potentially aiding in the prevention of atherosclerosis and obesity-related disorders.

Traditional Medicinal Uses

In Traditional Chinese Medicine, Alisma plantago-aquatica (Ze Xie) is used to:

• Promote urination and resolve dampness
• Treat edema, dysuria, and urinary tract infections
• Clear heat from the kidneys and bladder
• Support weight loss by addressing water retention
• Help in formulas targeting dizziness, vertigo, and lipid imbalances

Recommended Usage

• Rhizome Decoction: 6–15 grams of dried rhizome boiled in water daily.
• Standardized Extracts: Available in capsule or tablet form; follow product-specific dosing.
• Combination Formulas: Often combined with Poria cocos, Atractylodes, and other herbs for water metabolism and metabolic health.

Note: Long-term use should be supervised by a healthcare professional.

Safety and Side Effects

• Pregnancy and Lactation: Use cautiously; not recommended without professional supervision.
• Mild Side Effects: Rare but may include dry mouth, dizziness, or gastrointestinal upset.
• Traditional Cautions: Avoid in cases of yin deficiency with dryness, according to TCM principles.

Frequently Asked Questions (FAQs)

What is Alisma plantago-aquatica used for?
Traditionally to promote urination, clear damp heat, support kidney and bladder health, and regulate lipids.

Can it help with weight loss?
It may assist weight management by promoting diuresis and improving fluid metabolism.

Is it good for urinary tract infections?
Yes, it supports urinary health and has mild antimicrobial properties beneficial for UTI prevention.

Can it lower cholesterol?
Studies indicate that Alisma can help lower total cholesterol and LDL while improving HDL levels.

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