
Fructus Corni: Traditional Fruit for Kidney Vitality, Liver Health, and Anti-aging Support
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Fructus Corni, also known as Cornelian Cherry or Shan Zhu Yu in Traditional Medicine, is the fruit of Cornus officinalis. For centuries, it has been prized as a major tonic herb for strengthening the kidneys, preserving essence (jing), and stabilizing internal systems weakened by aging or chronic illness.
Modern pharmacological studies confirm that Fructus Corni possesses antioxidant, hepatoprotective, anti-inflammatory, and endocrine-supporting properties, making it valuable for metabolic health, reproductive vitality, and overall resilience.

Table of contents
Phytochemical Composition
Fructus Corni is rich in active compounds, including:
- Iridoid Glycosides (e.g., loganin, morroniside): Offer kidney protection, antioxidant, and anti-inflammatory benefits.
- Organic Acids (e.g., malic acid, gallic acid): Support liver detoxification and metabolic health.
- Triterpenoids and Flavonoids: Strengthen vascular health and provide antioxidant effects.
- Polysaccharides: Enhance immune modulation and cellular protection.

5 Key Health Benefits of Fructus Corni
1. Kidney Tonic and Vitality Booster

Fructus Corni nourishes kidney essence (jing) and supports adrenal function, traditionally used to treat symptoms like fatigue, frequent urination, and lower back weakness (Liu et al., 2018).
2. Liver Protection and Detoxification
Its iridoid glycosides protect liver cells against toxins and oxidative damage, support liver detox pathways, and help manage chronic liver conditions such as hepatitis and fatty liver (Zhang et al., 2017).
3. Anti-aging and Antioxidant Effects
Rich in flavonoids and triterpenoids, Fructus Corni combats oxidative stress, delays cellular aging, and supports skin, bone, and cognitive health, making it an important herb for longevity (Chen et al., 2020).
4. Blood Sugar and Lipid Regulation

Fructus Corni improves glucose metabolism, enhances insulin sensitivity, and helps regulate cholesterol levels, contributing to cardiovascular and metabolic wellness.
5. Immune Modulation and Hormonal Balance
Polysaccharides and iridoids from Fructus Corni modulate immune responses, enhance resilience against infections, and help balance hormones related to reproductive health and endocrine regulation.
Traditional Medicinal Uses
In Traditional Chinese Medicine, Fructus Corni (Shan Zhu Yu) is used to:
- Tonify kidneys and stabilize essence
- Strengthen the liver and regulate qi
- Treat frequent urination, incontinence, and seminal leakage
- Manage dizziness, tinnitus, and lumbar soreness
- Support recovery from chronic illness and aging-related decline
Recommended Usage
- Fruit Decoction: 6–15 grams of dried fruit boiled in water daily.
- Powdered Extract: Available as capsules or granules; follow product-specific dosing.
- Combination Formulas: Often paired with Rehmannia, Dioscorea, and Alisma in classical yin-tonifying formulas.
Note: Preparation often involves mild steaming or wine-processing to enhance the tonic properties.
Safety and Side Effects
- Pregnancy and Lactation: Generally safe under professional supervision.
- Mild Side Effects: Rare; may include digestive upset if overdosed.
- Traditional Cautions: Use cautiously in cases of internal dampness and heat excess according to TCM theory.
Frequently Asked Questions (FAQs)
What is Fructus Corni used for?
Primarily to tonify the kidneys, strengthen the liver, stabilize essence, and support vitality and aging health.
Is it helpful for frequent urination or incontinence?
Yes, it is traditionally used to stabilize the kidneys and reduce excessive leakage of fluids.
Does it protect the liver?
Yes, studies show it helps prevent liver damage and supports detoxification.
Is it safe for long-term use?
Generally yes, especially when used in proper therapeutic doses under healthcare supervision.
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References:
Liu, Y., et al. (2018). Protective effects of Fructus Corni extracts on kidney and reproductive function. Phytomedicine, 44, 47–55. https://doi.org/10.1016/j.phymed.2017.11.004
Zhang, L., et al. (2017). Hepatoprotective and antioxidant activities of iridoid-enriched extract from Cornus officinalis. International Journal of Molecular Sciences, 18(5), 1027. https://doi.org/10.3390/ijms18051027
Chen, Y., et al. (2020). Anti-aging effects of Fructus Corni: Modulation of oxidative stress and mitochondrial function. Frontiers in Pharmacology, 11, 561990. https://doi.org/10.3389/fphar.2020.561990
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